Fig. 3

The effect of ZnPc1-PDT on the spontaneous migration of HUVECs was evaluated using a wound healing assay. (a) Images were taken at 0, 5, 12, and 24Â h, and (b) the wound closure was quantified. At 24Â h, the wounds in the untreated cells and the dark group (w/o PDT) were completely closed. However, PDT treatment significantly inhibited the wound closure ability of HUVECs in a dose-dependent manner. Scale bar: 1Â mm.