Fig. 4

Differential metabolites. (A) Changes in the levels of 10 differential metabolites among the LSIL and HSIL groups (P value details can be found in the supplementary materials). (B) The performance of the 10-metabolite panel for HR-HPV-infected cervical lesions was assessed using the area under the curve (AUC) calculated by the random forest algorithm. The metabolite panel distinguished between the NILM group and the SIL group (LSIL + HSIL), yielding an AUC of 0.811. (C) The metabolite panel distinguished between the LSIL group and the HSIL group, with an AUC of 0.928.