Fig. 10 | Scientific Reports

Fig. 10

From: Unphosphorylated STAT1 binds to the BST2 transcription promoter, promoting increased AKBA anchoring on HPMECs to alleviate ARDS

Fig. 10

AKBA alleviates CLP-induced lung tissue damage in mice via U-STAT1/BST2. (A, B) LC3 expression was determined by relative quantification of immunofluorescence, using CD31 as an internal reference, (200×magnification), n = 5. (C) Statistical analysis of Western blot of U-STAT1 in mouse lung tissues, n = 5. (D) Statistical analysis of Western blot of BST2 in mouse lung tissues, n = 5. (E) Statistical analysis of Western blot of Bad in mouse lung tissues, n = 5. (F) Western blot analysis of BST2, U-STAT1, YP-STAT1, Bad, using β-actin expression as the internal reference. n = 5. (G, H) The apoptosis level of mouse lung tissue was evaluated by TUNEL kit, n = 5. *p < 0.05, **p < 0.01 and ***p < 0.001.

Back to article page