Fig. 1
From: Preterm birth increases susceptibility to hyperglycemia induced glomerular alterations in male mice
Structural alterations in preterm mouse kidneys exposed to hyperglycemia. Preterm and term mice were exposed to STZ at six weeks of age and euthanized at 18 weeks of age (a). The preterm diabetic group (PT-D) had a lower podocyte density than the term non-diabetic group (T-ND) (b). Preterm nondiabetic, term diabetic and preterm diabetic groups had lower proximal tubule fractions than the term diabetic group. Each datapoint represents a measurement from one image. Ten to fourteen images were captured in the subcapsular region of each of the kidneys (c). Preterm diabetic mice had more atubular glomeruli than preterm non-diabetic and term non-diabetic mice (d). Mann Whitney test (b, c, d) with a p-value<0.05 was considered statistically significant. A one-sided t-test was used to compare T-D to PT-D in b. Panel a was created in BioRender.com.
