Fig. 5
From: Preterm birth increases susceptibility to hyperglycemia induced glomerular alterations in male mice
Cellular communication analysis indicates weaker podocyte and endothelial cell interactions. Signaling interaction scores in term diabetic and preterm diabetic groups were evaluated by expression of ligand/receptor pairs in cells within the kidneys using CellChat. Heatmaps represent (left) the number of interactions and (right) interaction strength (adjusted according to cell number in the diabetic condition. (b) the circle plots represent cell-cell communication networks. The width of the edges indicates the strength of the communication. (c) The predicted outgoing and incoming signaling patterns in term diabetic and preterm diabetic groups and summarized as a heatmap. The color intensity represents differential interaction strength. Three most significant pathways are highlighted in the red box.
