Fig. 3

Trends in constituent ratios of ESCA stratified by clinical characteristics. (a) Constituent ratios of upper ESCA and ESCA at other segments from 2004–2015. (b) Constituent ratios of cervical ESCA and upper-third ESCA from 2004–2015. (c) Changes in the ages of patients with upper ESCA from 2004–2015. (d) Constituent ratios of total ESCA patients stratified by histologic type from 2004–2015. (e) Constituent ratios of patients with ESCA at other segments stratified by histologic type from 2004–2015; (f) Constituent ratios of patients with upper ESCA stratified by histologic type from 2004–2015. AAPC an average annual percent change with P < 0.05 was considered statistically significant.