Table 2 Demographics and clinicopathologic characteristics of upper ESCA.
Level | Overall | Validation cohort | Train cohort | P value | |
|---|---|---|---|---|---|
n | 1371 | 408 | 963 | ||
Age (median [IQR]) | 65.00 [58.00, 72.00] | 65.00 [58.00, 72.00] | 65.00 [58.00, 72.00] | 0.791 | |
Sex (%) | Female | 459 (33.5) | 132 (32.4) | 327 (34.0) | 0.565 |
Male | 912 (66.5) | 276 (67.6) | 636 (66.0) | ||
Marital status (%) | Abnormal | 681 (49.7) | 208 (51.0) | 473 (49.1) | 0.528 |
Normal | 690 (50.3) | 200 (49.0) | 490 (50.9) | ||
Site (%) | Upper third | 980 (71.5) | 278 (68.1) | 702 (72.9) | 0.074 |
Cervical | 391 (28.5) | 130 (31.9) | 261 (27.1) | ||
Histologic type (%) | Squamous | 1199 (87.5) | 353 (86.5) | 846 (87.9) | 0.526 |
Adenocarcinoma | 127 (9.3) | 43 (10.5) | 84 (8.7) | ||
Other | 45 (3.3) | 12 (2.9) | 33 (3.4) | ||
Grade (%) | I | 90 (6.6) | 25 (6.1) | 65 (6.7) | 0.272 |
II | 740 (54.0) | 215 (52.7) | 525 (54.5) | ||
III | 524 (38.2) | 166 (40.7) | 358 (37.2) | ||
IV | 17 (1.2) | 2 (0.5) | 15 (1.6) | ||
T stage (%) | 1 | 435 (31.7) | 134 (32.8) | 301 (31.3) | 0.846 |
2 | 138 (10.1) | 37 (9.1) | 101 (10.5) | ||
3 | 442 (32.2) | 132 (32.4) | 310 (32.2) | ||
4 | 356 (26.0) | 105 (25.7) | 251 (26.1) | ||
N stage (%) | No | 731 (53.3) | 215 (52.7) | 516 (53.6) | 0.764 |
Yes | 640 (46.7) | 193 (47.3) | 447 (46.4) | ||
M stage (%) | No | 1150 (83.9) | 343 (84.1) | 807 (83.8) | 0.902 |
Yes | 221 (16.1) | 65 (15.9) | 156 (16.2) |
