Table 2 Patient characteristics and treatment data (univariable per-patient analyses).
From: Prevalence and impact of ECMO cannula colonization: a single center study
Variable ↓ (all patients included in analyses) | All (n = 58) | Sterile (n = 28) | Colonized (n = 30) | Statistics |
|---|---|---|---|---|
Age (years), median (IQR) | 58.1 (52.4–62.9) | 58.8 (52.6–68.1) | 57.6 (51.5–60.2) | p = 0.24M |
SOFA score, median (IQR) | 10 (9–13) | 11 (9–13) | 9 (8–14) | p = 0.26M |
Multiple organ failure, n (%) | 17 (29.3) | 8 (28.6) | 9 (30.0) | OR 1.07, p > .99F 95% CI 0.32–3.05 |
Body mass index (kg/m2), median (IQR) | 27.7 (24.7–29.6) | 27.5 (24.2–28.6) | 27.7 (26.0–32.8) | p = 0.09M |
Male gender, n (%) | 45 (77.6) | 21 (75.0) | 24 (80.0) | OR 1.33, p = 0.76F 95% CI 0.39–4.47 |
Diabetes mellitus, n (%) | 17 (29.3) | 7 (25.0) | 10 (33.3) | OR 1.50, p = 0.57F 95% CI 0.46–4.54 |
Immunosuppression, n (%) | 50 (86.2) | 22 (78.6) | 28 (93.3) | OR 3.82, p = 0.14F 95% CI 0.81–19.6 |
AB0 blood group 0, n (%) | 22 (37.9) | 12 (42.9) | 10 (33.3) | OR 0.67, p = 0.59F 95% CI 0.23–1.86 |
COVID-19 ARDS, n (%) | 35 (60.3) | 13 (46.4) | 22 (73.3) | OR 3.17, p = 0.06F 95% CI 1.12–8.67 |
CPR/cardiogenic shock/pulmonary embolism, n (%) | 15 (25.9) | 10 (35.7) | 5 (16.7) | OR 0.36, p = 0.14F 95% CI 0.11–1.31 |
Non-COVID-19 ARDS, n (%) | 7 (12.1) | 4 (14.3) | 3 (10.0) | OR 0.67, p = 0.82F 95% CI 0.16–2.71 |
Septic shock, n (%) | 1 (1.7) | 1 (3.6) | 0 (0) | OR 0.00, p = 0.48F 95% CI 0.00–8.40 |
V-V, n (%) | 38 (65.5) | 16 (57.1) | 22 (73.3) | OR 2.06, p = 0.27F 95% CI 0.70–5.66F |
V-A, n (%) | 14 (24.1) | 10 (35.7) | 4 (13.3) | OR 0.28, p = 0.07F 95% CI 0.09–0.96 |
V-AV or multiple, n (%) | 6 (10.3) | 2 (7.1) | 4 (13.3) | OR 2.00, p = 0.67F 95% CI 0.43–11.1 |
RRT or PLEX while on ECMO, n (%) | 12 (20.7) | 6 (21.4) | 6 (20.0) | OR 0.92, p > 0.99F 95% CI 0.27–3.12 |
Occlusive CHX dressing, n (%) | 23 (39.7) | 10 (35.7) | 13 (43.3) | OR 1.38, p = 0.60F 95% CI 0.50–3.99 |
Time in hospital until ECMO start (days), median (IQR) | 7.0 (1.0–16.3) | 6.5 (2–15.5) | 9.5 (1–16.3) | p = 0.99M |
Duration ECMO run (days), median (IQR) | 15.5 (8.0–30.3) | 12.0 (4.3–27.8) | 20.0 (13.0–37.0) | p = 0.02M |
Cannulation scenario | ||||
|---|---|---|---|---|
Variable ↓ (patients with all analyzed cannulas inserted on d0 of ECMO run included in analyses) | All (n = 53) | Sterile (n = 26) | Colonized (n = 27) | |
During CPR, n (%) | 5 (9.4) | 4 (15.4) | 1 (3.7) | OR 0.21, p = 0.19F 95% CI 0.02–1.50 |
During or after CPR, n (%) | 7 (13.2) | 5 (19.2) | 2 (7.4) | OR 0.34, p = 0.25F 95% CI 0.06–1.92 |
Cannulation problems, n (%) | 10 (18.9) | 2 (7.7) | 8 (29.6) | OR 5.05, p = 0.08F 95% CI 0.96–25.11 |
Off hours (6 p.m. to 8 a.m.), n (%) | 20 (37.7) | 9 (34.6) | 11 (40.7) | OR 1.29, p = 0.78F 95% CI 0.42–3.90 |
Out of hospital, n (%) | 2 (3.8) | 1 (3.8) | 1 (3.7) | OR 0.96, p > 0.99F 95% CI 0.05–18.9 |
Referring hospital, n (%) | 28 (52.8) | 9 (34.6) | 19 (70.4) | OR 4.49, p = 0.01F 95% CI 1.45–14.0 |
ECMO center, n (%) | 23 (43.4) | 16 (61.5) | 7 (25.9) | OR 0.22, p = 0.01F 95% CI 0.07–0.69 |
