Table 1 Annotation of potential serum biomarkers in KKAy mice.
From: Anti-diabetes activity of (R)-gentiandiol in KKAy type 2 mice
No. | RT/min | m/z | Adducts | Formula | Error/ppm | Compound | Mass fragments | M vs C |
|---|---|---|---|---|---|---|---|---|
1 | 1.23 | 167.0158 | M-H | C5H4N4O3 | 1.27 | Uric acid | 124.0212;69.0100;41.9978 | ↑ |
2 | 1.31 | 179.0556 | M-H | C6H12O6 | 0.93 | d-Galactose | 89.0248;59.0641 | ↑ |
3 | 5.36 | 179.1000 | M-H | C6H12O6 | 1.97 | d-Glucose | 89.1440;70.2332;59.0120 | ↑ |
4 | 2.11 | 147.0770 | M + H | C5H10N2O3 | 1.93 | d-Glutamine | 101.0715;84.0449;56.0500 | ↓ |
5 | 5.57 | 180.0399 | M-H | C9H11NO3 | 2.03 | l-Tyrosine | 119.0350;72.0661 | ↑ |
6 | 3.22 | 118.0809 | M + H | C5H11NO2 | 2.39 | l-Valine | 72.0868 | ↑ |
7 | 5.32 | 132.0182 | M + H | C6H13NO2 | -1.78 | l-Leucine | 111.1007 | ↑ |
8 | 5.77 | 279.0099 | M-H | C18H32O2 | 2.55 | Linoleic acid | 128.2334 | ↓ |
9 | 5.53 | 193.0290 | M + H | C6H8O7 | -2.41 | Citric acid | 133.0031;115.0348;61.0137 | ↑ |
10 | 5.99 | 482.3237 | M-H | C23H48NO7P | 4.92 | LysoPC(15:0) | 184.0728;104.1067 | ↑ |
11 | 6.32 | 552.3918 | M + H | C28H58NO7P | 3.33 | LysoPC(20:0) | 534.0733;184.1070;104.4024 | ↑ |
12 | 6.01 | 281.3122 | M-H | C18H34O2 | 1.40 | Oleic acid | 263.2488 | ↓ |
13 | 7.35 | 105.0441 | M + H | C4H8O3 | -1.92 | (R)-3-Hydroxybutyric acid | 87.0335;69.0546 | ↑ |
14 | 10.00 | 120.0555 | M + H | C4H9NO3 | 4.37 | l-Threonine | 102.0290;56.0606 | ↑ |
15 | 11.34 | 76.0293 | M + H | C2H5NO2 | 1.98 | Glycine | 58.0344;30.0399 | ↓ |
