Fig. 2

Mean staining intensity (MSI) in tissue sections immunohistochemically stained with anti-CEACAM5, anti-TMPRSS4, anti-COL17A1, anti-CLDN18, and AQP5. (a) MSI for CEACAM5 expression. (b) MSI for TMPRSS4 expression. (c) MSI for COL17A1 expression. (d) MSI for CLDN18 expression. (e) MSI for AQP5 expression. Thick lines indicate medians, boxes represent the interquartile ranges (IQRs), whiskers indicate theĀ 95% confidence intervals (CI), and circles data from individual patients. Horizontal bars indicate significance levels (Mann-Whitney U-test: ***, pā<ā0.001; **, pā<ā0.01; *, pā<ā0.05; N.S.; not significant). Tissue types: PDAC: pancreatic ductal adenocarcinoma, Panc: pancreas, CP: chronic pancreatitis, DUO: duodenal tissue.