Fig. 3

Paired analysis of the mean staining intensities (MSIs) of targets in tissue sections from patients with both pancreatic ductal adenocarcinoma (PDAC) and pancreas (Panc) tissue available. (a) MSI for CEACAM5 expression. (b) MSI for TMPRSS4 expression. (c) MSI for COL17A1 expression. (d) MSI for CLDN18 expression. (e) MSI for AQP5 expression. Dots and lines represent data from individual patients. Thick lines indicate medians and boxes represent interquartile ranges (IQRs). Horizontal bars indicate significance levels (Wilcoxon-signed rank test: ***, pā<ā0.001; **, pā<ā0.01; *, pā<ā0.05; N.S.; not significant). (f) Heat map showing the T/N ratios (MSI PDAC/MSI Panc) for patients with available PDAC and Panc data. Gray regions indicate missing data.