Fig. 7
From: NAT10 promotes hepatocellular carcinoma progression by modulating the ac4C-DDIAS-PI3K-Akt axis
The schematic below depicts the role NAT10 plays in modulating PI3K/Akt signaling in HCC progression. (A, B) CCK8 assay was used to examine the reversal effect of DDIAS overexpression on proliferative capacity of shNAT10 HCC cells.(C, D) Transwell assays were used to determine the reversal effects of DDIAS overexpression on the migratory (C) and invasive (D) capacities of shNAT10 cells. Scale bar: 100 μm (E) Western blot analysis was conducted to assess the impact of DDIAS overexpression on the protein levels of key Akt pathway components in hepatocellular carcinoma cells.
