Table 2 Laboratory Findings at Admission.

Blood routine

 Red blood cell count

(2.3–5.8) × 10^12/L

3.79 (3.290, 4.160)

3.765 (3.313, 4.170)

3.67 (3.060, 4.260)

0.8988

0.652

0.4722

 Hemoglobin

130–175 g/L

111 (75.50, 130.5)

111 (96.00, 128.0)

109 (89.00, 124.0)

0.7061

0.9342

0.5846

 White blood cell count

(3.5–9.5) × 10^9/L

6.93 (5.015, 10.14)

11.81 (9.143, 16.08)

9.28 (6.380, 13.50)

0.0002**

0.0948

0.0287*

 Neutrophil count

(1.8–6.3) × 10^9/L

6.11 (3.890, 10.12)

10.7 (8.200, 16.40)

7.8 (5.240, 11.60)

0.0068*

0.3653

0.0093**

 Lymphocyte count

(1.1–3.2) × 10^9/L

1.34 (0.820, 1.755)

0.88 (0.475, 1.453)

0.52 (0.290, 0.800)

0.0532

 < 0.0001***

0.0065**

 Eosinophil count

(0.02–0.52) × 10^9/L

0.145 (0.0625, 0.2175)

0.01 (0.000, 0.110)

0.01 (0.000, 0.050)

0.0122*

0.0026*

0.4143

 Basophil Count

(0.00–0.06) × 10^9/L

0.03 (0.015,0.045)

0.02 (0.000, 0.045)

0.01 (0.000, 0.030)

0.2482

0.0967

0.6671

 Platelet count

(125–350) × 10^9/L

223 (169.0, 309.0)

204.5 (131.5, 280.5)

173 (119.0, 249.0)

0.4129

0.2033

0.5847

Blood biochemistry

 Blood urea nitrogen

2.5–7.1 mmol/L

5 (3.455, 10.05)

6.065 (4.623, 9.903)

8.7 (5.215, 12.86)

0.2437

0.1326

0.1763

 Serum creatinine

62–115 μmol/L

59 (53.00,87.95)

70.2 (53.00, 107.1)

75 (59.10, 100.4)

0.5274

0.3056

0.6044

 Alkaline phosphatase (ALP)

45–125 IU/L

93.5 (54.25, 123.0)

100 (72.00, 163.0)

78 (62.00, 117.5)

0.2881

0.8101

0.0599

 Alanine aminotransferase (ALT)

9–50 IU/L

19 (11.00, 49.50)

45.5 (14.75, 107.8)

26 (19.00, 56.00)

0.0472*

0.3168

0.2263

 Aspartic transaminase (AST)

15–40 IU/L

39.5 (14.50, 39.50)

109.8 (27.00, 109.8)

57 (22.07, 57.00)

0.0125*

0.1767

0.0601

 Total bilirubin (TBIL)

4.7–24 μmol/L

12.8 (8.700, 15.05)

13.7 (8.800, 22.10)

12 (9.825, 18.73)

0.5410

0.7991

0.6672

 Total protein (TP)

60–83 g/L

67(59.94,73.00)

58 (54.00,66.00)

57.07 (53.00,63.00)

0.0270*

0.007**

0.3570

 Prealbumin

200–430 mg/L

125 (59.50, 210.1)

87.8 (43.75,198.8)

89 (65.00,137.0)

0.3312

0.2397

0.8529

 Albumin

35–55 g/L

34.1(28.60,38.35)

33 (28.00,34.00)

31 (27.08, 33.48)

0.2170

0.1527

0.387

 Triglyceride (TG)

0.38–1.88 mmol/L

1.08 (0.970,1.500)

1.67 (1.000,2.350)

1.28 (1.075, 2.088)

0.3162

0.6254

0.2204

 Total cholesterol (TC)

3.35–5.69 mmol/L

4.26(2.070,5.030)

3.145 (2.820, 3.883)

2.88 (2.153, 3.983)

0.4910

0.1735

0.2365

 High density lipoprotein cholesterol (HDL-C)

0.91–2.1 mmol/L

0.78 (0.470,1.000)

0.66 (0.610, 0.840)

0.755 (0.450, 1.093)

0.7667

0.9193

0.7242

 Low density lipoprotein cholesterin (LDL-C)

0–3.33 mmol/L

2.85(1.210,3.360)

1.88(1.510,2.400)

1.455 (1.013, 2.490)

0.3339

0.1101

0.1810

 Blood glucose

3.89–5.83 mmol/L

4.7(4.190,7.400)

7.29 (5.550,8.383)

7.8 (5.790,10.10)

0.1648

0.0867

0.4250

 Glycosylated hemoglobin (HbA1c)

5.65 (5.350,6.175)

6.05 (5.700,11.88)

6.25 (5.400,7.875)

0.1719

0.381

0.5402

Blood electrolytes

 K + 

3.50–5.10 mmol/L

3.995(3.465,3.995)

4.08(3.410,4.080)

4.438(3.688,4.438)

0.6981

0.0626

0.0768

 Na + 

130–147 mmol/L

140(138.0,141.6)

137.6(136.0, 141.8)

139.0(135.9,144.9)

0.4825

0.9363

0.5320

 Cl−

99–110 mmol/L

105(101.0,106.0)

101.7(99.00, 105.3)

103(99.90, 106.5)

0.1344

0.3558

0.4096

 Ca2 + 

2.00–2.52 mmol/L

2.22(1.950,2.310)

1.965(1.880,2.163)

2.02(1.960,2.110)

0.0175*

0.0743

0.242

 P2−

0.85–1.51 mmol/L

1.06(0.770,1.330)

1.1 (0.8700,1.380)

0.99 (0.7450,1.280)

0.6764

0.5742

0.1876

 Mg2 + 

0.7—1.0 mmol/L

0.855(0.7925,0.9600)

0.83(0.7900,0.9500)

0.82(0.7650,0.9650)

0.7769

0.7286

0.8964

Arterial blood gas (ABG)

 PaO2

83–108 mmHg

90(81.01, 108.8)

83.4(63.75,102.4)

89.2(69.00,119.5)

0.3301

0.8375

0.3474

 SpO

93.0–98.0%

96.9(95.00,99.00)

97.35 (93.13, 98.70)

97.6(95.70,99.23)

0.8323

0.6351

0.3991

 PaCO2

35–45 mmHg

39.45(35.00,41.00)

38(32.25,40.67)

38.22(34.25,46.25)

0.8149

0.5509

0.4129

 PH

7.35–7.45

7.44(7.430,7.450)

7.43(7.373,7.475)

7.39(7.360,7.460)

0.6735

0.2014

0.3591

 BEb

− 3.0–3.0 mmol/L

1.2(− 0.3000,2.800)

1.33 (− 1.800,4.800)

− 0.19(− 3.100,3.900)

0.8621

0.9610

0.5622

 Standard bicarbonate (SB)

22–26 mmol/L

26(24.75,27.03)

24.4(22.00,28.40)

24.3(21.70,28.00)

0.6527

0.5238

0.7020

 Actual bicarbonate (AB)

22–26 mmol/L

25.95(24.75,27.25)

25.9(22.40,28.40)

27.1(22.90,28.60)

0.8853

0.8644

0.8234

 Lactic acid

0.5–1.6 mmol/L

0.9(0.600,1.500)

1.65(1.031,2.770)

1.062(1.000,1.661)

0.0109*

0.1147

0.0164*

Coagulation indicators

 PT

10.0–16.0 s

12.7(12.00,17.20)

13.6(12.70,15.20)

13.7(12.63,16.38)

0.6157

0.5126

0.5848

 INR

/

1.08(1.040,1.740)

1.16(1.100,1.300)

1.155(1.073,1.395)

0.4041

0.6947

0.8717

 APTT

22.3–38.7 s

30.2(26.50,38.40)

30.8(27.53,36.55)

31.9(27.03,38.88)

0.7696

0.5954

0.7229

 Fibrin degradation product (FDP)

0–5 mg/L

3.05(2.500,6.800)

9.7(4.615,17.05)

14.14(7.600,25.25)

0.0069**

0.0009**

0.1621

 D-dimer quantification

 < 0.55 mg/L

0.93(0.3250,2.503)

2.42(1.450,4.930)

3.42(1.890,6.450)

0.0110*

0.0034**

0.3176

 TT

14.00–21.00 s

16(14.40,18.50)

15.8(14.90,16.95)

16.3(15.35,17.83)

0.4406

0.7293

0.1281

 Fg

1.8–3.5 g/L

4.495(2.452,6.000)

5.16(2.400,7.240)

4.85(3.768,6.455)

0.6257

0.2757

0.2757

Myo-cardial enzymonram

 PRO-BNP

5–349 pg/mL

102(40.30,374.4)

288(104.0,1115)

628.3(168.8,988.7)

0.0612

0.0117*

0.3176

 Hypersensitive troponin I(cTnT)

 < 0.1 μg/L

2.7(0.011,8.150)

0.077(0.0145,4.308)

5.8(0.070,32.60)

0.7607

0.1118

0.0143*

 Creatine kinase

22–269 IU/L

48.5(25.25,67.50)

61(22.00,200.0)

54.5(34.00,115.3)

0.4340

0.3610

0.9597

CK-MB

0.3–4 ng/mL

1.1(0.800,2.050)

3.3(0.900,9.000)

2.5(1.150,5.250)

0.0206*

0.0372*

0.4187

 Myoglobin

0-58 ng/mL

21.1(15.85, 54.05)

61.7(28.70, 236.4)

90(28.25, 281.6)

0.0233*

0.0076**

0.6020

 Lactic dehydrogenase (LDH)

120–250 IU/L

187.6(166.5,293.5)

281(202.5,406.0)

251.5 (199.0,396.8)

0.0744

0.0515

0.8579

Cellular immunity

 CD3^ ( +)

47.98–82.6%

74(61.16,81.91)

68.03(55.34,77.95)

66.22(56.15,73.00)

0.3917

0.2327

0.5177

 CD3^ ( +) CD4^ ( +)

24.15–51.66%

47.65(20.06,51.53)

38.41(34.54,48.85)

39.2(30.40,48.35)

0.8648

0.8228

0.6584

 CD3^ ( +) CD8^ ( +)

14.24–41.48%

30.1(16.13,41.43)

23.94(11.43,37.95)

23.3(16.99,26.30)

0.5162

0.3124

0.8849

 CD4^ ( +) /CD8^ ( +)

1.00–2.50

1.84(1.130,3.435)

1.45(1.000,2.810)

1.51(1.225,1.968)

0.7427

0.4950

0.9132

 CD3 absolute count

713–2368 cells/μl

797(294.0,1488)

555.5(416.3,919.8)

446(270.0,608.5)

0.6599

0.3193

0.4228

CD4 absolute count

384–1346 cells/μl

492(161.8,1002)

260(235.0,590.0)

307(133.5,380.0)

0.6116

0.2827

0.5261

 CD8 absolute count

220–1110 cells/μl

306(116.4, 451.5)

152(120.0,237.5)

144(61.00,229.0)

0.3980

0.1893

0.3875

Inflammatory indicators

 CRP

 < 10 mg/L

29(7.075,81.03)

107.5(20.10,166.0)

88.7(54.43,149.0)

0.0683

0.0464*

0.6781

 PT

 < 0.50 ng/mL

0.12(0.030,0.520)

0.38(0.200,7.120)

0.33(0.150,1.440)

0.0276*

0.0514

0.3876

 IL-6

 < 5.4 pg/mL

21.1(9.225,43.79)

36.87(4.225,113.5)

52.55(25.95,162.2)

0.659

0.1059

0.3696

 IL-1β

 < 3.1 pg/mL

7.36(2.850,19.17)

5(2.400,8.900)

4(2.400,5.225)

0.5243

0.4959

0.9349

 IL-2 receptor

 < 5.71 pg/mL

1751(4.260,4314)

1095(2.440,1720)

1300(189.8,3368)

0.2606

0.7394

0.6280

 IL-8

 < 20.6 pg/mL

40.5(2.400,659.4)

36.1(2.400,94.25)

18.15(2.400,52.63)

1.000

0.8038

0.7487

 IL-10

 < 12.9 pg/mL

2.7(2.440, 90.00)

5(2.440, 8.000)

5(3.350, 13.85)

0.8040

0.3946

0.4469

 TNF

 < 16.5 pg/mL

7.76(2.980,57.15)

7.435(2.400,13.00)

9.9(3.825,12.73)

0.8020

0.9714

0.8495

Serum immunoglobulin

 IgG

8.6–17.4 g/L

9.81(6.998,16.08)

11.75(9.178,14.60)

9.525(7.550,11.85)

0.5495

0.6590

0.0793

 IgM

1–4.2 g/L

1.675(1.268,2.188)

03.535(0.3625,1.528)

0.845(0.4050,1.755)

0.0426*

0.1093

0.4928

 IgA

0.3–2.2 g/L

2.615(1.608,3.185)

2.02(1.413,2.788)

2.325(1.690,3.058)

0.5728

0.8411

0.5699

 IgE

5.0–165.3 IU/L

28(10.55,56.68)

114.8(25.30,228.8)

178(67.40,344.0)

0.1179

0.0150*

0.3669

Other indicators

 β-D-1, 3-glucan (fungus)

 < 60 pg/mL

10(10,10)

19(10,35.90)

28.76(10,85.79)

0.0142*

0.0056**

0.1905

0(0%)

4(9.3%)

6(18.50%)

0.2366

0.0823

0.2339

 GM test (Aspergillus galactomannan detection)

 < 0.25 ng/mL

0.11(0.1,0.13)

0.1(0.0365,0.214)

0.11(0.100,0.150)

0.5113

0.9456

0.4262

0(0%)

2(4.65%)

3(9.25%)

0.4114

0.2360

0.4173