Fig. 8 | Scientific Reports

Fig. 8

From: A bioinformatics-driven approach to identify biomarkers and elucidate the pathogenesis of type 2 diabetes concurrent with pulmonary tuberculosis

Fig. 8

Comparative bioinformatic analyses of immune cell enrichment in the PTB + T2DM and HC groups. (A-B) Enrichment scores of 22 distinct immune cell types in the two groups (PTB with T2DM vs. Healthy control and PTB with T2DM vs. T2DM group). (C) Correlation analysis between six key genes in PTB + T2DM and various immune cell types. (D) PCA was performed using the PCA expression plot feature in RStudio, data dimensionality of the data set was reduced, allowing the creation of a two-dimensional scatter plot for an initial sample distribution assessment. (E) Spearman’s correlation analysis of C1QA and LINC00278 expression with M2 macrophages. The values on the x-axis represent the relative enrichment level of M2 macrophages, and the values on the y-axis represent the expression levels of C1QA and LINC00278.

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