Table 2 Fluorescence spectroscopy was employed for obtaining thermodynamic parameters at temperatures of 290, 298, and 308 K.

From: Insights into the interaction of Fibrinogen with Timolol Maleate and elucidation of binding sites via. spectroscopic and molecular docking study

Temperature

Binding constant (Kb)

Lmol–1

binding sites

(n)

Gibbs’s energy change (ΔG)

Kcal/mol

ΔH

Kcal/mol

ΔS

Kcal/mol

290 K

1.45 × 102

0.6

− 6.609

66.963

253.81

298 K

6.05 × 102

0.7

− 8.736

66.963

253.81

308 K

2.798 × 103

0.9

− 11.181

66.963

253.81

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