Fig. 3 | Scientific Reports

Fig. 3

From: ANXA2 regulates mitochondrial function and cellular senescence of PDLCs via AKT/eNOS signaling pathway under high glucose conditions

Fig. 3

The effect of high glucose and ANXA2 on ROS production and mitochondrial morphology of PDLCs. PDLCs were transfected with pcDNA3.1-ANXA2 or its empty vector controls, followed by treatment with high glucose. (A) The ROS accumulation of PDLCs. (B) Semi-quantitative analysis of ROS accumulation. (C) Representative images of mitochondrial morphology. All data are presented as the means ± SEM from three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001. CTRL: Control; 40G: 40mM glucose; 40G-A: 40mM glucose + ANXA2 overexpression.

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