Fig. 1

Progression of the COVID-19 pandemic in the Czech Republic in 2021 and 2022. The timeline of pandemic restrictions (Supplementary Table 3) and key points of the vaccination campaign are overlaid over the 7-day running average of daily confirmed cases (blue). Newly introduced restrictions are shown as dates with red outlines, while the lifting of specific restrictions is shown as dates in green, with notable points of the vaccination campaign in yellow. Descriptions of these restrictions are found in Supplementary Table 3. The 7-day running average number of samples sequenced (green), by date of collection, shows the available sequencing capacity as the sequencing network was formalised and came online in 2021.