Fig. 2

Restricted cubic splines demonstrating the relationship between the probability of mitral annular calcification (A) age (B) body-mass index (C) systolic blood pressure (D) left atrial volume index. The reference values for each variable were determined using the optimal cut-off points for receiver operating characteristic curves (Figure S4). Adjustments were made for age, body-mass index, diabetes, systolic blood pressure, and left atrial volume index. MAC, mitral annular calcification; OR, odds ratio; BMI, body-mass index; SBP, systolic blood pressure; HbA1c, glycated hemoglobin; LAVI, left atrial volume index.