Fig. 3

EAAT-2 genetic and molecular characteristics in ACP and CNP groups. (A) EAAT-2 genotype distribution bar graph showing the frequency of different EAAT-2 genotypes (A/A, A/C, C/C) in ACP and CNP groups. (B) Lower EAAT-2 mRNA expression (2^−ΔCt) is showed in CNP group. (C) Lower EAAT-2 protein concentration is shown in CNP group. (D) Higher glutamate levels is shown in CNP group.

*, p < 0.05; **, p < 0.01; ***, p < 0.001; A/A, two identical “A” alleles; C/A, one “C” allele and one “A” allele; C/C, two identical “C” alleles.