Fig. 1
From: Similarities and differences between natural sleep and urethane anesthesia
Similarities and differences in slow network activity during natural sleep and under urethane anesthesia. (A) Local field potentials (LFPs) recorded in the deactivated state (dU) of urethane anesthesia at the surface (surf, upper trace), layer V (middle trace) of parietal cortex (PAC), and stratum radiatum (CA1 rad) of the dorsal hippocampus. (B) LFPs in NREM sleep recorded at the same depths as in A. (C) Time–frequency distribution (TFD) of 10 s periods of surface LFP during dU (upper graph) and NREM sleep (lower graph). (D) Normalized (norm., see Methods) power spectrum of surface PAC LFP in dU (red) and NREM sleep (black), averaged across 12 animals (mean ± standard errors) displayed in logarithmic scaling. Power in the lower δ range is similar in dU compared to NREM as shown in E. (E) Average voltage depth profiles (N = 6 animals) of slow oscillation (SO: 0.1–1.5 Hz, left graph) and δ (1.5–4 Hz) activity (middle graph) in dU, and δ activity in NREM sleep (right graph). (F) Mean changes in voltage (left and phase (right, N = 6 animals) with depth during dU (red) and NREM (black). Note the similarities between SO and δ activity in dU and the difference from δ activity in NREM sleep. Contributions from volume conduction of signals from distant locations can not be excluded, neither in dU nor in NREM.
