Fig. 2 | Scientific Reports

Fig. 2

From: Similarities and differences between natural sleep and urethane anesthesia

Fig. 2

Similarities and differences in activated (θ) network activity during natural sleep and under urethane anesthesia. (A) Local field potentials (LFPs) recorded in the activated state of urethane anesthesia (aU) at the surface (surf, upper trace), layer V (middle trace) of parietal cortex (PAC) and stratum radiatum (CA1 rad) of the dorsal hippocampus. (B) LFPs recorded in tonic REM sleep at the same depths as in A. Note the different amplitude scales in A and B. (C) Time–frequency distribution (TFD) of 10 s periods of CA1 rad LFP during aU (upper graph) and tonic REM sleep (lower graph). (D) Mean normalized (norm., see Methods) power spectra at CA1 rad in aU (red, N = 6 animals) and tonic REM sleep (black, N = 10 animals). (E) Average voltage depth profiles (N = 6 animals) of 3.5–6 Hz θ in aU (left graph) and 4.5–12 Hz θ in tonic REM sleep (right graph). (F) Mean changes in voltage (left, N = 6 animals) and phase (right, N = 6 animals) with depth during aU (red) and REM (black). Note the abrupt phase shift observed in aU compared to the more gradual phase shift in REM sleep.

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