Fig. 5
From: Chronic rejection models for vascularized composite tissue allotransplantation
Histopathological scores of the transplanted grafts. A. Stacked column graph of perivascular mononuclear cell infiltration in the superficial and deep dermis (0; < 10cells/vessel, 1; 10–25 cells/vessel, 2; 26–50 cells/vessel, 3; > 50cells/vessel). B, Stacked column graph of perivascular mononuclear cell dermal infiltrate area expressed as percent area occupied by the most involved dermal vessels at 40 × (0; < 25%, 1; 25–50%, 2; 50–75%, 3; > 75%). C, Stacked column graph of mononuclear cell infiltrate into epidermis (0; < 10 cells per 4, 20 × fields, 1; 10–20 cells per 4, 20 × fields, 2; > 20 cells per 4, 20 × fields, and 3; transdermal infiltrate). D, Stacked column graph of epidermal necrosis as presence of keratinocyte apoptosis and necrosis (0; none, 1; apoptosis, 2; focal necrosis, 3; sloughed). E, Stacked column graph of BANFF rejection scores. F, G, and H, Stacked column graph of adnexal atrophy, dermal fibrosis, and mast cell counts in the dermis, respectively (0; none, 1; minimal, 2; mild, 3; moderate, 4; severe). Pooled data from 3 independent experiments. Syngeneic; n = 3, acute; n = 10, chronic KO; n = 7, and chronic BM12; n = 9.
