Fig. 7
From: Chronic rejection models for vascularized composite tissue allotransplantation
Evaluation of chronic allograft vasculopathy (CAV). CAV was defined as the simultaneous occurrence of intimal thickening and endarteritis. A, H&E-stained image of arteries from different rejection models. Scale bar; 100 µm in syngeneic, acute, and chronic KO images, 200 µm in the chronic BM12 image. B, Stacked column graphs of intimal arteritis (mononuclear cells underneath arterial endothelium; 0; none, 1; < 25%, 2; > 25%, 3; transmural involvement, intimal thickening (0; none, 1; < 25%, 2; 25–50%, 3; > 50%), and CAV. Pooled data from 3 independent experiments. Syngeneic; n = 3, acute; n = 7, chronic KO; n = 4, and chronic BM12; n = 7.
