Fig. 4 | Scientific Reports

Fig. 4

From: Polydatin exerts therapeutic effects on myelodysplastic syndrome by inhibiting the protein expression of oncogenes via hypermethylation in vitro

Fig. 4

PD inhibited the protein expression of PIK3CA, ITPR3 and SPOPL in SKM-1 cells. (A) A PPI network constructed via the STRING database and visualized by Cytoscape. PIK3CA, ITPR3 and SPOPL were identified as the hub genes in red. (B) Protein expression bands of PIK3CA, ITPR3 and SPOPL following PD treatment for 48 h. Grayscale values of PIK3CA (C), ITPR3 (D) and SPOPL (E). *p < 0.05, **p < 0.01.

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