Table 5 Covariate-adjusted comparison of finger-tapping severity across four states: medication (on, off) and DBS (on, off).

From: Medication versus globus pallidus internus deep brain stimulation in Parkinson’s disease with deep learning video analysis of finger tapping

 

\(p\) Value

All four states

Med off vs.

Med on

DBS off

vs.

DBS on

Med off

vs.

DBS off

Med off

vs.

DBS on

Med on vs.

DBS on

Amplitude

Mediana ↑

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

0.59

\(\:<\)0.001*

0.48

IQRb ↓

0.02

–

–

–

–

–

Minimumb ↑

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

0.28

\(\:<\)0.001*

0.12

Maximuma ↑

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

0.97

\(\:<\)0.001*

0.79

Entropya ↓

\(\:<\)0.001*

\(\:<\)0.001*

0.34

0.02

0.001*

0.26

Speed

Mediana ↑

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

IQRa ↑

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

0.11

Minimumb ↔

0.07

–

–

–

–

–

Maximumb ↑

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

0.01

Acceleration

Medianb ↔

0.1

–

–

–

–

–

IQRb ↑

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

Minimumb ↓

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

Maximumb ↑

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

\(\:<\)0.001*

Aperiodicitya ↓

0.26

–

–

–

–

–

Period

Medianb ↓

\(\:<\)0.001*

\(\:<\)0.001*

0.03

\(\:<\)0.001*

\(\:<\)0.001*

0.87

IQRb ↓

\(\:<\)0.001*

\(\:<\)0.001*

0.05

0.002*

\(\:<\)0.001*

0.47

Minimumb ↓

0.005

–

–

–

–

–

Maximumb ↓

\(\:<\)0.001*

\(\:<\)0.001*

0.34

\(\:<\)0.001*

\(\:<\)0.001*

0.13

Entropyb ↓

\(\:<\)0.001*

\(\:<\)0.001*

0.05

0.001*

\(\:<\)0.001*

0.34

Fatigueb (set n = 78)c ↓

0.31

–

–

–

–

–

Freezeb (set n = 56)c ↓

0.01

–

–

–

–

–

  1. DBS, deep brain stimulation. IQR, interquartile range.
  2. aParametric variables.
  3. bNonparametric variables converted to ranks for analysis.
  4. cComputed using 78 sets for fatigue and 56 for freeze parameter.
  5. * Significant p values. P values < 0.05/21 for the ‘All four states’ column. P values < 0.05/5 for all other columns comparing two different states.
Back to article page