Table 2 Bivariable and multivariable logistic regression analyses for factors associated with CL infection in Northeast Ethiopia (March 2022-May 2023).

From: Molecular epidemiology, distribution, and determinants of cutaneous leishmaniasis in Northeast Ethiopia

Variables

Categories

ITS1-PCR

COR (95% CI)

p-value

AOR (95% CI)

p-value

Positive,

n (%)

Negative.

n (%)

Age group (years)

< 9

32 (80.0)

8(20.0)

2.98 (1.28–6.91)

0.011

2.94 (1.21–7.14)

0.018*

9 to 19

139 (80.3)

34 (19.7)

3.04 (1.84–5.02)

< 0.001

3.23 (1.89–5.51)

< 0.001*

> 19

82 (57.3)

61 (42.7)

1

 

1

 

The presence of animals in the house

Yes

163 (76.2)

51 (23.8)

1.85 (1.16–2.94)

0.010

2.06 (1.23–3.43)

0.006*

No

90 (63.4)

52 (36.6)

1

 

1

 

Family size

< 5

136 (63.3)

79 (36.7)

1

 

1

 

> 5

117 (83.0)

24 (17.0)

2.83 (1.69–4.76)

< 0.001

2.78 (1.60–4.84)

< 0.001*

The presence of a cave near the human settlement and gorge within 300 m

Yes

188 (68.4)

87 (31.6)

0.53 (0.3–0.97)

0.040

0.88 (0.4–1.83)

0.732

No

65 (80.2)

16 (19.8)

1

 

1

 

Hyrax near 300 m

Yes

214 (69.0)

96 (31.0)

0.4 (0.17–0.93)

0.033

0.81 (0.28–2.33)

0.689

No

39 (84.8)

7 (15.2)

1

 

1

 

Animal burrow near home

Yes

208 (68.0)

98 (32.0)

0.24(0.1–0.6)

0.003

0.44 (0.12–1.67)

0.230

No

45 (90.0)

5 (10.0)

1

 

1

 

Animal dung near home

Yes

224 (69.3)

99 (30.7)

0.3(0.11–0.9)

0.033

0.65 (0.17–2.57)

0.538

No

29 (87.9)

4 (12.1)

1

 

1

 

Immediate neighbor with ulcerating disease

Yes

159 (66.8)

79 (33.2)

0.5(0.3–0.87)

0.013

0.91 (0.39–2.11)

0.824

No

94 (79.7)

24 (20.3)

1

 

1

 

Sharing residence with a household member with typical skin lesions

Yes

123 (64.7)

67 (35.3)

0.51 (0.3–0.82)

0.005

0.62 (0.290–1.31)

0.211

No

130 (78.3)

36 (21.7)

1

 

1

 
  1. LCL localized cutaneous leishmaniasis, MCL mucocutaneous leishmaniasis; Mucosal leishmaniasis, DCLd iffuse CL, IM intramuscular, LR leishmaniasis recidivan, IQR interquartile range.
  2. *Significant at p < 0.05.