Fig. 7 | Scientific Reports

Fig. 7

From: A novel allosteric GCase modulator prevents Tau accumulation in GBA1WT and GBA1L444P/L444P cellular models

Fig. 7

Viability of rat hippocampal primary neurons treated for 2 days with GT-02216 at the indicated concentration or with BDNF before being challenged with 5 µmol/L Tau oligomers for 1d. Cell viability was assessed with the MTT assay (mean ± SD, n = 3–4 wells). Ordinary 1way ANOVA (p < .0001) and Dunnett’s multiple tests against the control, **** p < .0001.

Back to article page