Fig. 5

(A) SHG/THG, Hematoxylin and eosin (H&E) staining images, and fiber orientation maps of frozen sections from healthy skin and three types of scar tissue. Scale bar 100 \(\upmu\)m. Total area is \(1 \times 0.8\,\hbox {mm}^2\). (B) Fiber orientation distribution and (C) fiber mask. (D) Quantitative analysis of the standard deviation of fiber orientation distribution and fiber density of healthy skin (n=5) and scar skin (n=7).