Table 2 Lung volume (cm3) and human predictive factor (HPF) lung volume and human predictive factor (HPF) values in patients with and without radiation-induced lung injury (RILI). Mean, standard deviation (SD), median, minimum, and maximum values are reported. Statistical significance was assessed using the Mann–Whitney U-test. Patients with RILI had significantly lower lung volumes and HPF values, indicating a potential link between these parameters and radiation-induced fibrosis risk.

From: Machine learning-driven imaging data for early prediction of lung toxicity in breast cancer radiotherapy

Parameter

RILI status

Mean

Std. Dev

Median

Min

Max

p-value

Effect size (r)

Lung volume (V cm3)

No

1680.30

450.75

1667.1

693.6

2964.8

0.003

0.19

Yes

1532.47

466.57

1453.97

668.1

2794.3

  

HPF

No

0.14

0.07

0.13

0.03

0.35

< 0.001

0.25

Yes

0.11

0.05

0.10

0.

0.3