Table 2 The correlation of LANCL2 expression and expression of immune cell markers in STAD. (*P < 0.05, **P < 0.01, ***P < 0.001).
Immune Cell | Gene markers | STAD | |||
---|---|---|---|---|---|
None | Purity | ||||
Correlation | P | Correlation | P | ||
B cell | CD19 | −0.040980935 | ns | −0.000842639 | ns |
MS4 A1 | −0.116967372 | * | −0.079447643 | ns | |
CD38 | 0.037157829 | ns | 0.073164508 | ns | |
CD8 + T Cell | CD8 A | 0.013772817 | ns | 0.043250989 | ns |
CD8B | 0.100908819 | * | 0.137365638 | ** | |
Tfh | CXCR5 | −0.078614122 | ns | −0.036049935 | ns |
ICOS | 0.098511269 | * | 0.137158518 | ** | |
BCL6 | −0.13462622 | ** | −0.115364799 | * | |
Th1 | IL12RB2 | 0.181070367 | *** | 0.205165074 | *** |
IL27RA | 0.127373373 | ** | 0.167489088 | ** | |
TBX21 | −0.01478229 | ns | 0.025116584 | ns | |
Th2 | CCR3 | 0.006022922 | ns | 0.042646863 | ns |
STAT6 | 0.231906398 | *** | 0.221304525 | *** | |
GATA3 | −0.066249614 | ns | −0.03716759 | ns | |
Th9 | TGFBR2 | −0.023159528 | ns | −0.015674413 | ns |
IRF4 | 0.010051242 | ns | 0.053174536 | ns | |
SPI1 | −0.058214967 | ns | −0.025436138 | ns | |
Th17 | IL21R | 0.109812158 | * | 0.157164957 | ** |
IL23R | 0.121360167 | * | 0.133727656 | ** | |
STAT3 | 0.056679897 | ns | 0.06850112 | ns | |
Th22 | CCR10 | −0.064024828 | ns | −0.045149489 | ns |
AHR | 0.143796771 | ** | 0.145190406 | ** | |
Treg | FOXP3 | 0.114811084 | * | 0.157182535 | ** |
CCR8 | 0.081715518 | ns | 0.113283818 | * | |
IL2RA | 0.025612651 | ns | 0.062370861 | ns | |
T cell exhaustion | PDCD1 | 0.103973922 | * | 0.149885288 | ** |
CTLA4 | 0.129464346 | ** | 0.171537265 | *** | |
Macrophage | CD68 | 0.033670636 | ns | 0.030071114 | ns |
ITGAM | −0.026382789 | ns | −0.004152963 | ns | |
M1 | NOS2 | 0.114316132 | * | 0.110433882 | * |
ROS1 | 0.134924626 | ** | 0.146250148 | ** | |
M2 | ARG1 | 0.087928747 | ns | 0.094382794 | ns |
MRC1 | 0.00302229 | ns | 0.01248608 | ns | |
TAM | HLA-G | 0.048539652 | ns | 0.05138024 | ns |
CD80 | 0.08436522 | ns | 0.11793013 | * | |
CD86 | −0.02894429 | ns | −0.002584883 | ns | |
Monocyte | CD14 | −0.030455351 | ns | −0.016272615 | ns |
FCGR3 A | 0.015060074 | ns | 0.023851848 | ns | |
NK | XCL1 | 0.126273445 | * | 0.135659098 | ** |
KIR3DL1 | 0.024643389 | ns | 0.036420718 | ns |