Table 1 Patients’ baseline characteristics.

From: Systematic screening for primary immunodeficiencies in patients hospitalized for severe infection in pediatric intensive care unit

 

N = 46

Sex, n (%)

 Female

19 (41.30)

 Male

27 (58.70)

Age at admission (y), median (IQR)

2.88 (0.92; 7.01)

Infection severity estimates

 Intensive care duration (d), median (IQR)

3 (2; 5)

 Post-surgery admission, n (%)

7 (15.22)

 Familial history of PID or similar clinical signs, n (%)

2 (4.34)

 Familial consanguinity, n (%)

3 (6.52)

 Relevant personal medical history, n (%)

3 (6.52)

 Type 1 neurofibromatosis

1 (2.17)

 Cystic adenomatoid pulmonary malformation

1 (2.17)

 Rheumatoid purpura

1 (2.17)

 Poor nutritional status before infection (weight ≤ -2SD), n (%)

5 (10.87)

 Complete vaccination schedule, n (%)

30 (65.22)

DTP

45 (97.83)

 13-valent conjugate pneumococcal vaccine

42 (91.30)

 HBV

42 (91.30)

 MMR

43 (93.47)

 Meningococcal C vaccine

32 (69.56)

Positive PID screening score, n (%)

 JMF

0 (0.00)

 DSAI

4 (8.70)

 CEREDIH

5 (10.87)

Time of follow up (months), median (IQR)

 First follow-up consultation

4.92 (3.40; 6.70)

 Second follow-up consultation

23.40 (14.50; 28.23)

  1. DTP, Diphteria tetanus and poliomyelitis vaccine; HBV, hepatitis B virus vaccine; MMR, measles, mumps, and rubella vaccine; JMF, Jeffrey Modell Foundation; DSAI, the 12 warning signs of the German Patients’ Organization for Primary Immunodeficiencies; CEREDIH, French Reference Center for Hereditary Immunodeficiencies.