Fig. 2

Multimodal imaging features of DWP. (A–C) Fundus photographs demonstrate DWP as darker areas in true-color, red channel, and red-free imaging. (D) Swept-source optical coherence tomography (SS-OCT) confocal scanning superluminescent ophthalmoscopy (cSSO) image. (E) SS-OCT horizontal B scan (red box in panel D) shows disappearance of ellipsoid zone (EZ) and interdigitation zone reflective signals in the DWP region (left of white arrow), with dilated choroidal vessels. (F) Adaptive optics (AO) fundus image (red box in panel D) demonstrates loss of cone masic reflectance in the DWP area (left of yellow dashed line). (G–I) Optical coherence tomography angiography (OCTA) images. Vascular perfusion in the DWP region remains intact in the superficial vascular complex (SVC) layer, but is significant reduced in both the deep capillary plexus (DCP) and outer retinal layer. (J–L) En face SS-OCT images. Reflectivity of DWP lesion is unchanged in the ganglion cell complex (GCC) layer, slightly decreased in the inner nuclear (INL) layer, and markedly reduced in the outer retinal layer.