Table 2 Univariate analysis and multivariate analysis based on TIMM8A expression and clinical characteristics.
Characteristics | Total(N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
T stage | 1079 | ||||
T1 | 276 | Reference | |||
T2 | 629 | 1.332 (0.887–1.999) | 0.166 | 0.840 (0.442–1.597) | 0.595 |
T3&T4 | 174 | 1.953 (1.221–3.123) | 0.005 | 0.789 (0.366–1.700) | 0.545 |
N stage | 1063 | ||||
N0 | 514 | Reference | |||
N1&N2&N3 | 549 | 2.239 (1.567–3.199) | < 0.001 | 1.387 (0.826–2.328) | 0.216 |
M stage | 922 | ||||
M0 | 902 | Reference | |||
M1 | 20 | 4.254 (2.468–7.334) | < 0.001 | 3.115 (1.578–6.149) | 0.001 |
TIMM8A | 1082 | 1.471 (1.085–1.993) | 0.013 | 1.742 (1.095–2.770) | 0.019 |
PAM50 | 1042 | ||||
LumA | 561 | Reference | |||
LumB | 204 | 1.663 (1.088–2.541) | 0.019 | 1.189 (0.732–1.932) | 0.485 |
Her2 | 82 | 2.261 (1.325–3.859) | 0.003 | 1.691 (0.913–3.134) | 0.095 |
Basal | 195 | 1.285 (0.833–1.981) | 0.257 | 0.967 (0.510–1.836) | 0.919 |
Pathologic stage | 1059 | ||||
Stage I | 180 | Reference | |||
Stage II | 619 | 1.699 (0.986–2.926) | 0.056 | 1.735 (0.697–4.320) | 0.237 |
Stage III&Stage IV | 260 | 3.596 (2.059–6.280) | < 0.001 | 2.938 (0.982–8.791) | 0.054 |
Histological type | 977 | ||||
Infiltrating Ductal Carcinoma | 772 | Reference | |||
Infiltrating Lobular Carcinoma | 205 | 0.827 (0.526–1.299) | 0.410 | ||
