Table 3 Multiple logistic regression analysis of the association between hysterectomy, menopause, and TL with CHD risk (Participants without history of the mentioned reproductive factors were indicated as the reference group).

Variables		Multiple logistic regression
Variables		OR (95% CI)	P-value
Model-1	Hysterectomy	1.45 (0.98–2.13)	0.062
	Menopause	1.81 (1.17–2.79)	0.007
	Tubal ligation	1.37 (1.05–1.80)	0.022
Model-2	Hysterectomy	1.31 (0.88–1.96)	0.181
	Menopause	1.61 (1.03–2.53)	0.037
	Tubal ligation	1.35 (1.02–1.78)	0.037
Model-3	Hysterectomy	1.40 (0.94–2.10)	0.101
	Menopause	1.59 (1.01–2.50)	0.045
	Tubal ligation	1.29 (0.97–1.71)	0.076
Model-4	Hysterectomy	1.40 (0.94–2.10)	0.102
	Menopause	1.55 (0.98–2.44)	0.058
	Tubal ligation	1.27 (0.96–1.68)	0.097
Model-5	Hysterectomy	1.31 (0.87–1.97)	0.190
	Menopause	1.52 (0.96–2.40)	0.075
	Tubal ligation	1.05 (0.78–1.41)	0.763
Model-6	Hysterectomy	1.32 (0.87–1.99)	0.187
	Menopause	1.50 (0.95–2.40)	0.083
	Tubal ligation	1.02 (0.75–1.38)	0.901
Model-7	Hysterectomy	1.21 (0.80–1.85)	0.368
Model-8	Menopause	1.43 (0.88–2.31)	0.144
Model-9	Tubal ligation	1.01 (0.74–1.37)	0.956

Participants without history of these reproductive factors were indicated as the reference group. Model-1: Adjusted by age, Model-2: Adjusted by age, DM, and HTN, Model-3: Adjusted by age, DM, HTN, and residential place, Model-4: Adjusted by age, DM, HTN, residential place, and WHR, Model-5: Adjusted by age, DM, HTN, residential place, and WHR, and number of pregnancies, Model-6: Adjusted by age, DM, HTN, place, WHR, Pregnancy number, Social economic, Education level, MET, and occupation, Model-7: Adjusted by age, DM, HTN, residential place, WHR, pregnancy number, socio-economic level, education level, MET, occupation, menopause, and TL, Model-8: Adjusted by age, DM, HTN, residential place, WHR, pregnancy number, socio-economic level, education level, MET, occupation, hysterectomy, and TL, and Model-9: Adjusted by age, DM, HTN, residential place, WHR, pregnancy number, socio-economic level, education level, MET, occupation, hysterectomy, and menopause.

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