Table 2 Basic data and comparison among each group.
Group 1 (20–29) | Group 2 (30–39) | Group 3 (40–49) | Group 4 (50–59) | Group 5 (60–69) | Group 6 (70–79) | ×2 / F | P-value | ||
|---|---|---|---|---|---|---|---|---|---|
Gender (Female, n (%)) | 2 (40%) | 3 (60%) | 2 (40%) | 2 (40%) | 3 (60%) | 2 (40%) | 1.071 | 0.957 | |
BMI, Mean ± SD | 25.3 ± 6.6 | 23.3 ± 2.6 | 25.4 ± 1.4 | 21.7 ± 2.7 | 22.7 ± 3.8 | 21.1 ± 1.7 | 1.282 | 0.304 | |
Duration of symptoms(M), Median(UQ ~ LQ) | 5.0 (1.8 ~ 10.0) | 3.0 (2.0 ~ 24.0) | 6.0 (3.2 ~ 6.0) | 2.0 (0.7 ~ 8.0) | 3.0 (1.5 ~ 15.0) | 1.0 (0.7 ~ 8.5) | 0.764 | 0.584 | |
Pre-VAS, Mean ± SD | 6.2 ± 1.9 | 7.0 ± 0.7 | 9.0 ± 0.7 | 9.0 ± 0.7 | 8.4 ± 0.9 | 8.4 ± 0.5 | 6.248 | 0.001** | |
Pre-ODI, Mean ± SD | 47.2 ± 18.7 | 57.2 ± 4.1 | 79.6 ± 9.4 | 85.2 ± 3.9 | 78.4 ± 8.0 | 74.8 ± 6.9 | 11.327 | < 0.001** | |
Pre-JOA, Mean ± SD | 16.2 ± 4.9 | 14.0 ± 1.4 | 10.4 ± 2.5 | 10.2 ± 1.8 | 10.6 ± 2.6 | 11.0 ± 1.0 | 4.189 | 0.007** | |
Post-VAS, Median(UQ ~ LQ) | 1.0 (0.0 ~ 2.0) | 1.0 (0.0 ~ 1.5) | 1.0 (1.0 ~ 1.5) | 2.0 (2.0 ~ 2.0) | 2.0 (0.5 ~ 3.0) | 2.0 (1.5 ~ 3.0) | 2.075 | 0.104 | |
Post-ODI, Median(UQ ~ LQ) | 2.0 (0.0 ~ 8.0) | 4.0 (0.0 ~ 9.0) | 4.0 (3.0 ~ 7.0) | 16.0 (9.0 ~ 21.0) | 8.0 (5.0 ~ 19.0) | 14.0 (11.0 ~ 27.0) | 5.032 | 0.003** | |
Post-JOA, Mean ± SD | 27.4 ± 1.7 | 26.2 ± 3.1 | 25.6 ± 1.3 | 21.4 ± 1.7 | 23.4 ± 3.6 | 21.8 ± 3.0 | 4.603 | 0.004** | |
JOA improvement rate (%), Mean ± SD | 88.4 ± 10.8 | 82.4 ± 19.0 | 81.6 ± 7.2 | 59.7 ± 7.9 | 68.1 ± 22.5 | 59.8 ± 17.0 | 3.359 | 0.019* | |
Autophagy intensity – high, n (%) | 4 (80%) | 4 (80%) | 3 (60%) | 2 (40%) | 0 (0%) | 0 (0%) | 13.710 | 0.018* | |
– Low, n (%) | 1 (20%) | 1 (20%) | 2 (40%) | 3 (60%) | 5 (100%) | 5 (100%) | |||
Pfirrmann classification – III, n (%) | 3 (60%) | 3 (60%) | 2 (40%) | 0 (0%) | 0 (0%) | 0 (0%) | 21.700 | 0.017* | |
– IV, n (%) | 2 (40%) | 2 (40%) | 3 (60%) | 4 (80%) | 3 (60%) | 1 (20%) | |||
– V, n (%) | 0 (0%) | 0 (0%) | 0 (0%) | 1 (20%) | 2 (40%) | 4 (80%) | |||
MSU classification – II, n (%) | 3 (60%) | 3 (60%) | 5 (100%) | 4 (80%) | 5 (100%) | 4 (80%) | 5.000 | 0.416 | |
– III, n (%) | 2 (40%) | 2 (40%) | 0 (0%) | 1 (20%) | 0 (0%) | 1 (20%) | |||
CCI classification – (0–1) | 4 (80%) | 4 (80%) | 4 (80%) | 2 (40%) | 1 (20%) | 3 (60%) | 6.667 | 0.247 | |
– (≥ 2) | 1 (20%) | 1 (20%) | 1 (20%) | 3 (60%) | 4 (80%) | 2 (40%) | |||