Fig. 2

Construction of a voxel-based tibia model: (a) a set of raw micro-CT images of a 16-week-old mouse tibia, (b) processed micro-CT images: The raw images were processed using necessary tools such as flipping, rotating, resizing, cropping, and converting to black and white. An appropriate threshold was chosen to capture the bone cross-section. (c) Rendered 3D mouse tibia with brick elements (hexahedral elements) for finite element analysis.