Table 1 Comparison of clinical and ultrasound data of benign and malignant patients with NML between training group and validation group.

Age, Median (Q1, Q3)

40 (34, 49)

48 (42.5, 54)

26840^b

 < 0.001

41 (34, 49)

47 (39, 53)

5874.5^b

 < 0.001

High, Median (Q1, Q3)

160 (158, 165)

160 (158, 165)

45174^b

0.567

160 (158, 165)

160 (158, 164)

8635.5^b

0.386

Weigh, Median (Q1,Q3)

62 (57, 70)

60 (56, 67.67)

49,475.5^b

0.009

63 (57, 70)

61.01 (56, 68)

9440.5^b

0.026

BMI, Median (Q1, Q3)

1.66 (1.59, 1.74)

1.64 (1.57, 1.72)

49,133.5^b

0.014

1.682 ± 0.126

1.644 ± 0.124

2.419^b

0.016

Menarche age, Median (Q1, Q3)

12 (12, 13)

12 (12, 13)

41930^b

0.248

12 (12, 13)

12 (12, 12.75)

8448.5^b

0.492

Menopause, n (%)

26.542^c

 < 0.001

9.547^c

0.002

 No

234 (86.989)

225 (68.807)

114 (88.372)

91 (72.222)

 Yes

35 (13.011)

102 (31.193)

15 (11.628)

35 (27.778)

Position, n (%)

12.06^c

0.007

10.077^c

0.018

 Outer upper quadrant

142 (52.788)

210 (64.220)

70 (54.264)

84 (66.667)

 Inner upper quadrant

63 (23.420)

61 (18.654)

25 (19.380)

28 (22.222)

 Outer lower quadrant

41 (15.242)

45 (13.761)

21 (16.279)

10 (7.937)

 Inner lower quadrant

23 (8.550)

11 (3.364)

13 (10.078)

4 (3.175)

 Long diameter, Median (Q1, Q3)

2 (1.1, 4.36)

2.54 (1.7, 3.8)

38,264.5^b

0.006

2.2 (1.4, 3.84)

2.8 (1.83, 3.8)

6991.5^b

0.054

 Wide diameter, Median (Q1, Q3)

0.9 (0.59, 1.6)

1.1 (0.8, 1.6)

36525^b

 < 0.001

1 (0.6, 1.7)

1.2 (0.9, 1.6)

6654.5^b

0.012

Focus orientation, n (%)

0.020^c

0.887

Fisher

1

 Parallel

261 (97.026)

319 (97.554)

126 (97.674)

123 (97.619)

 No parallel

8 (2.974)

8 (2.446)

3 (2.326)

3 (2.381)

Rear echo, n (%)

Fisher

 < 0.001

Fisher

 < 0.001

 No change

237 (88.104)

256 (78.287)

120 (93.023)

98 (77.778)

 Attenuation

27 (10.037)

71 (21.713)

7 (5.426)

28 (22.222)

 Enhancement

5 (1.859)

0 (0)

2 (1.550)

0 (0)

Calcification , n (%)

90.702^c

 < 0.001

45.974^c

 < 0.001

 No calcification

211 (78.439)

150 (45.872)

86 (66.667)

48 (38.095)

 Coarse calcification

28 (10.409)

22 (6.728)

24 (18.604)

9 (7.143)

 Fine calcification

30 (11.152)

155 (47.401)

19 (14.729)

69 (54.762)

Surrounding structure, n (%)

21.947^c

 < 0.001

20.787^c

 < 0.001

 No twist

147 (54.647)

115 (35.168)

71 (55.039)

33 (26.190)

 Twist

122 (45.353)

212 (64.832)

58 (44.961)

93 (73.810)

Blood flow characteristics, n (%)

48.509^c

 < 0.001

21.372^c

 < 0.001

 Grade 0

119 (44.238)

75 (22.936)

56 (43.411)

28 (22.222)

 Grade I

76 (28.253)

73 (22.324)

33 (25.581)

24 (19.048)

 Grade II

40 (14.870)

93 (28.440)

24 (18.605)

39 (30.952)

 Grade III

34 (12.639)

86 (26.300)

16 (12.403)

35 (27.778)

Peripheral blood flow, n (%)

2.636^c

0.104

Fisher

0.066

 None

257 (95.539)

321 (98.165)

122 (94.574)

125 (99.206)

 Yes

12 (4.461)

6 (1.835)

7 (5.426)

1 (0.794)