Table 2 Diagnostic efficacy of ECV, ALBI, and MELD-Na for controls and subclassified cirrhosis groups.
From: Estimating liver cirrhosis severity with extracellular volume fraction by spectral CT
AUC | Cutoff value | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Youden | ||
|---|---|---|---|---|---|---|---|---|
Control vs. cirrhosis | ECV | 0.911 (0.858 to 0.949) | 29.46 | 76.38 (68.0–83.5) | 95.56 (84.9–99.5) | 98.0 (92.9–99.8) | 58.9 (46.8–70.3) | 0.719 |
ALBI | 0.878 (0.819 to 0.923) | -2.65 | 80.31 (72.3–86.8) | 88.89 (75.9–96.3) | 95.3 (89.4–98.5) | 61.5 (48.6–73.3) | 0.692 | |
MELD_Na | 0.868 (0.810 to 0.911) | 6 | 88.98 (82.2–93.8) | 71.11 (55.7–83.6) | 89.7 (83.0–94.4) | 69.6 (54.2–82.3) | 0.601 | |
Child-Pugh A vs. B | ECV# | 0.901 (0.827 to 0.951) | 33.72 | 78.72 (64.3–89.3) | 87.93 (76.7–95.0) | 84.1 (69.9–93.4) | 83.6 (71.9–91.8) | 0.667 |
ALBI | 0.847 (0.764 to 0.910) | -1.87 | 57.45 (42.2–71.7) | 98.28 (90.8–100.0) | 96.4 (81.7–99.9) | 74.0 (62.8–83.4) | 0.557 | |
MELD_Na | 0.772 (0.680 to 0.848) | 8 | 78.72 (64.3–89.3) | 62.07 (48.4–74.5) | 62.7 (49.1–75.0) | 78.3 (63.6–89.1) | 0.408 | |
Child-Pugh B vs. C | ECV# | 0.966 (0.892 to 0.995) | 39.53 | 90.91 (70.8–98.9) | 95.74 (85.5–99.5) | 90.9 (70.8–98.9) | 95.7 (85.5–99.5) | 0.867 |
ALBI | 0.906 (0.811 to 0.963) | -1.5 | 81.82 (59.7–94.8) | 89.36 (76.9–96.5) | 78.3 (56.3–92.5) | 91.3 (79.2–97.6) | 0.712 | |
MELD_Na | 0.868 (0.764 to 0.937) | 12 | 86.36 (65.1–97.1) | 70.21 (55.1–82.7) | 57.6 (39.2–74.5) | 91.7 (77.5–98.2) | 0.566 |
