Fig. 3 | Scientific Reports

Fig. 3

From: Decreased expression of insulin-degrading enzyme increases gluconeogenesis and glucose production in cultured hepatocytes administered with glucagon

Fig. 3

Development and characterization of a mouse IDE knockdown cell line. Mouse hepatocytes (AML12) were transfected with an shRNA to knockdown Ide. (A) mRNA levels, (B) representative western blot image and quantification of the protein levels, and (C) assessment of the proteolytic activity of IDE. Results are mean ± SEM. n = 3 per group. *p value < 0.05 versus control by Students’ T-test.

Back to article page