Table 3 Pathophysiological alterations observed in liver cirrhosis.
Variables | Control | PK-Sim default | CP-A |
---|---|---|---|
Functional liver volumea | 1 | 2.2 | 0.81 |
Hematocrit (%)a | 40.9 | 0.47 | 36.6 |
Plasma protein factorb | – | 1 | 0.81 |
GFR (mL/min)a | 120 | 21.5 | 83.7 |
Blood flow (mL/min)b | |||
Liver | – | 18.83 | 1.3 |
Kidney | – | 228.58 | 0.88 |
Bone and other organs | – | – | 1.75 |