Fig. 5
No significant alteration in pro-inflammatory gene expression after treatment with antibacterial agents. Gene expression of cytokines/chemokines (IL-1β, TNF-α, CCL20, CXCL1), hBD-2 and TIMP-1 after application of antibacterial agents. The gene expressions were analyzed using qRT-PCR. The bar graph illustrates the gene expression levels of cytokines/chemokines (IL-1β, TNF-α, CCL20, CXCL1), hBD-2, and TIMP-1 in comparison to untreated controls after administration of various antibacterial agents. Data points (n = 18) were collected from six INTERbACT models under each experimental condition. The statistical significance was determined using the Kruskal–Wallis method, *p < 0.05 and **p < 0.01.
