Table 3 Performance of different screening strategies for diabetes in all study subjects.

From: Diagnosis of diabetes without oral glucose tolerance test is associated with increased mortality in older adults

 

Only FPG and HbA1c

Strategy 1* Any 1 MS components

Strategy 2† MS Component of

BP or WC

Strategy 3‡ 3 or more MS components

OGTT

0%

19.4%

17.6%

5.9%

NNS§

NA

4.0

3.8

2.3

Sensitivity

74.0%

89.9%

88.7%

80.7%

Specificity

100%

100%

100%

100%

PPV

100%

100%

100%

100%

NPV

96.8%

98.7%

98.6%

97.6%

  1. BP, blood pressure; MS, metabolic syndrome; NNS, numbers needed to screen; NPV, negative predictive value; OGTT, oral glucose tolerance test; PPV, positive predictive value; WC, waist circumference.
  2. *Strategy 1: age ≥ 60 years plus any one component of metabolic syndrome.
  3. †Strategy 2: age ≥ 60 years plus either the presence of blood pressure or waist circumference component of metabolic syndrome.
  4. ‡Strategy 3: age ≥ 60 years plus three or more components of metabolic syndrome.
  5. §Numbers of OGTT needed to diagnose one case of diabetes mellitus.
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