Fig. 4

Using the bilateral SMA and PCUN from the DC map as fingerprints, fMRI showed that FC was altered between groups. An independent sample t-test was performed between the LPE patients and NC groups (T maps threshold at pā<ā0.05, AlphaSim corrected). (A) The brain areas where FC was enhanced between the bilateral SMA and the right inferior frontal gyrus; (B) The brain areas where FC was dropped off between the bilateral PCUN and bilateral thalamus. (C) The ROC curves for distinguishing the two groups using the FC between the inferior frontal gyrus and SMA. The AUC was 0.82 (Pā=ā0.002). (D) The ROC curves for distinguishing the two groups using the FC between the precuneus and thalamus. The AUC was 0.83 (pā<ā0.001). ROI: region-of-interest SMA: SMA; PCUN: precuneus.