Fig. 3
From: Crosstalk of injured podocytes with parietal epithelial cells through Wnt4/β-Catenin signaling

Wnt4/β-Catenin pathway activation is stronger in male rats after induction of podocyte injury. Glomerular Wnt4 mRNA expression, as assessed by Real time-PCR using isolated rat kidney glomeruli, was higher in male compared to female rats after induction of podocyte injury (A). Wnt4-positive glomerular area was analyzed using immunohistochemistry (B). Relative glomerular β-Catenin mRNA expression was measured using Real-time PCR (C). *p < 0.05 **p < 0.01 ***p < 0.001.