Fig. 6 | Scientific Reports

Fig. 6

From: Dynamic changes in BDNF, VEGF, and GDNF after transplanting human protein-based scaffolds with Wharton’s Jelly MSCs in a rat brain injury model

Fig. 6

Analysis of rat neurotrophic and growth factors expression at mRNA level in the injured rat brain (OUA groups) at different time points (24 h, Day 7, Day 14, and Day 21) compared to the non-treated animals (control group). The relative expression level of the analysed genes was normalized to the value of GAPDH reference gene. Results are presented as a mean ± SD, with the control group set to a value of 1. The "*" symbol indicates comparison of the statistically significant difference in expression levels in the rat brain after injury versus control. The "#" symbol indicates comparison of the expression level in the rat brain at different time points after focal injury. Statistical analysis was performed using One Way ANOVA followed by Tukey’s multiple comparisons test (n = 12, samples collected from 4 animals analysed in triplicate; ***p < 0.001; ****p < 0.0001; #p < 0.05; ##p < 0.01; ###p < 0.001; ####p < 0.0001).

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