Fig. 1 | Scientific Reports

Fig. 1

From: Optogenetic restoration of high-sensitivity vision using ChRmine- and ChroME-based channelrhodopsins

Fig. 1

Immunohistochemistry of retinas treated with ChRmine, ChRmine-T119A, and ChroME2s AAVs. (a) Schematic of the AAV transgene cassettes. (b-d) Immunofluorescence stained-images of retinal sections. eGFP represents opsin expression in treated rd1 mice. Cone photoreceptors are labeled using CAR (b, red) and rod photoreceptors with RHO (c, red). (d) Co-localization of the opsin (eGFP) and Brn3a (red) confirm expression in ganglion cells. CAR = cone arrestin, RHO = rhodopsin, eGFP = enhanced green fluorescent protein.

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