Fig. 3
From: Optogenetic restoration of high-sensitivity vision using ChRmine- and ChroME-based channelrhodopsins
Light avoidance experiments in rd1 mice expressing ChRmine, ChRmine-T119A, or ChroME2s. (a) Schematic of light/dark box for light avoidance test based on Riebe and Wotjak, 201224. (b) Average change in side preference using white light (irradiance of 100 μW cm−2) in C57BL6/J (n = 26), ChRmine- (n = 29), ChRmine-T119A- (n = 8), ChroME2s- (n = 21), and PBS- (n = 19) injected mice. Statistical significance assessed with Welch’s ANOVA test with post-hoc Games-Howell HSD threshold matrix, *p < 0.05, **p < 0.01, ***p < 0.0001.
