Table 2 Delayed type hypersensitivity response in animals and corresponding percentage increase in paw volume to treatments after 4, 24, and 48 h.

From: In silico and in vivo assessment of the immunostimulatory activity of palmitic acid derived from Vernonia amygdalina

Groups

Doses (mg/kg)

Measure of paw thickness (hours post-treatment)

0

4

24

48

% increase

% increase

% increase

Palmitic acid

2

1.71 ± 0.1

2.89 ± 0.05*

69.0

2.15 ± 0.27

25.7

1.77 ± 0.11

3.5

Palmitic acid

5

1.76 ± 0.05

2.59 ± 0.11*

47.2

2.3 ± 0.09*

30.7

2.04 ± 0.19

15.9

Palmitic acid

10

1.67 ± 0.05

2.33 ± 0.10*

39.5

2.06 ± 0.09

23.4

1.81 ± 0.06

8.4

CONTROL

1.64 ± 0.23

2.43 ± 0.12*

48.2

2.2 ± 0.11*

34.1

2.07 ± 0.04*

26.2

CPE

50

1.84 ± 0.04

2.33 ± 0.12*

26.6

2.39 ± 0.06*

29.9

2.12 ± 0.09

15.2

Levamisole

50

1.58 ± 0.05

2.40 ± 0.18*

51.9

2.26 ± 0.11*

43.0

2.17 ± 0.08*

37.3

  1. CPE, Cyclophosphamide.
  2. *Indicates a significant difference compared with the control group (p < 0.05).