Fig. 3 | Scientific Reports

Fig. 3

From: CytoBead ANA 2 assay - a novel method for the detection of antinuclear antibodies

Fig. 3

CytoBead ANA 2 fluorescence images of antinuclear antibody (ANA) and ANA-specific autoantibody detection. (A) Negative HEp-2 cells (negative control) (B) Cytobead negative control demonstrating only fluorescence of evenly stained reference beads (13 μm) (upper arrow) with unstained SS-A/Ro-coated beats (lower arrow). (C) Positive HEp-2 cells (positive control). (D) Positive CytoBead ANA 2 determination of anti-SS-A/Ro antibody revealed by peripheral fluorescence staining of SS-A/Ro-coated microbeads (15 μm) (arrow).

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