Fig. 3 | Scientific Reports

Fig. 3

From: MiR-125b-5p ameliorates ventilator-induced lung injury in rats by suppressing ferroptosis via the regulation of the Keap1/Nrf2/GPX4 signaling pathway

Fig. 3

Overexpression of miR-125b-5p alleviates ferroptosis and lung tissue injury in VILI rats. (A,B) Expression of miR-125b-5p in the lung tissue of rats based on qRT-PCR. (C) Observation of the lung tissue with the naked eye. (D) Wet/dry weight ratio of the lung tissue. (E) Total protein content in BALF. (F) Lung tissue HE staining (200 × and 400 ×) based on observation with a light microscope and lung injury score. (**P < 0.01.***P < 0.001.****P < 0.0001). VILI, ventilator-induced lung injury; BALF, bronchoalveolar lavage fluid; HE, Hematoxylin and eosin; qRT-PCR, real-time quantitative polymerase chain reaction.

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